You can update your mobile number on your PAN card through the Income Tax e-filing portal by logging in, navigating to the 'My Profile' section, and selecting 'Profile Settings' to edit your contact information. Enter the new mobile number and verify it using the OTP sent to your new mobile and registered email. For a formal change in your PAN data, you can use the official NSDL (Protean) or UTIITSL portals. There, you must submit a 'Changes or Correction in existing PAN Data' request, select the mobile number for correction, and complete the process, often via Aadhaar-based e-KYC, for a nominal fee.
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