This historical drama is based on John Guy's biography Queen of Scots: The True Life of Mary Stuart. The plot chronicles the 1569 Revolt of the Northern Earls in England. Showcasing a prolonged battle for the throne, the film focuses on Mary Stuart's attempt to overthrow Elizabeth I, the Queen of England, also her cousin. The film also reunites actors Saoirse Ronan & Guy Pearce after a span of 12 years.